-
ligand binding domain (LBD) in an
intramolecular head-to-tail
interaction FXXLF motif;
where F = phenylalanine, L = leucine, and X = any
amino acid residue...
- to a
FxxLF motif contained in coactivators. Conversely,
antagonists destabilize the
agonist conformation of H12
blocking the
binding of the
FXXLF coactivator...
- "Electrostatic
Modulation in
Steroid Receptor Recruitment of
LXXLL and
FXXLF Motifs". Mol. Cell. Biol. 23 (6): 2135–50. doi:10.1128/MCB.23.6.2135-2150...
- de Vos C,
Trapman J,
Jenster G (November 2009). "Functional
screening of
FxxLF-like
peptide motifs identifies SMARCD1/BAF60a as an
androgen receptor cofactor...
- 0765. PMID 11818501. He B,
Minges JT, Lee LW,
Wilson EM (March 2002). "The
FXXLF motif mediates androgen receptor-specific
interactions with coregulators"...
- M108312200. PMID 11673464. He B,
Minges JT, Lee LW,
Wilson EM (Mar 2002). "The
FXXLF motif mediates androgen receptor-specific
interactions with coregulators"...
-
containing various signature motifs. ARs seem to have a
distinct preference for ‘
FxxLF’ type of
binding motifs (where F = phenylalanine, L = leucine, and X = any...
- "Electrostatic
modulation in
steroid receptor recruitment of
LXXLL and
FXXLF motifs".
Molecular and
Cellular Biology. 23 (6): 2135–2150. doi:10.1128/MCB...
-
promoting transcriptional through direct binding to the
androgen receptor FXXLF motif region. This
control is
specific to primates, and is due to a mutation...
- M111218200. PMID 11856738. He B,
Minges JT, Lee LW,
Wilson EM (March 2002). "The
FXXLF motif mediates androgen receptor-specific
interactions with coregulators"...
