- The
FKBPs, or FK506
binding proteins,
constitute a
family of
proteins that have
prolyl isomerase activity and are
related to the
cyclophilins in function...
- It is also
commonly referred to as
FKBP-12 or FKBP12 and is a
member of a
family of FK506-binding
proteins (
FKBPs). The
protein encoded by this gene is...
- organisms;
these DFIs are
natural chimera of CyP and
FKBPs,
fused in
either order (CyP-
FKBP or
FKBP-CyP).
Immunophilins act as
receptors for immunosuppressive...
-
proteins (
FKBPs) do not
normally form
dimers but can be
caused to
dimerize in the
presence of FK1012.
Genetically engineered proteins based on
FKBPs can be...
- 1 (mTORC1). mTOR has also been
called FRAP (
FKBP-rapamycin-****ociated protein), RAFT (rapamycin and
FKBP target), RAPT1, or SEP. The
earlier names FRAP...
-
functional antagonist to FKBP5 at
corticoid receptors FKBP3 - a DNA
binding FKBP GRCh38:
Ensembl release 89: ENSG00000096060 – Ensembl, May 2017 GRCm38: Ensembl...
-
derivative of the drug
tacrolimus (FK506), to
induce homo-dimerization of
FKBP. This
system was used in vivo to
induce binding between cell
surface receptors...
- TORC2 complex.
Plant species have TOR
proteins in the
protein kinase and
FKBP-rapamycin
binding (FRB)
domains that
share a
similar amino acid sequence...
- 1991). "Calcineurin is a
common target of cyclophilin-cyclosporin A and
FKBP-FK506 complexes". Cell. 66 (4): 807–15. doi:10.1016/0092-8674(91)90124-h...
- conditions.
Proteins with
prolyl isomerase activity include cyclophilin,
FKBPs, and parvulin,
although larger proteins can also
contain prolyl isomerase...
