Definition of Excitotoxicity. Meaning of Excitotoxicity. Synonyms of Excitotoxicity

Here you will find one or more explanations in English for the word Excitotoxicity. Also in the bottom left of the page several parts of wikipedia pages related to the word Excitotoxicity and, of course, Excitotoxicity synonyms and on the right images related to the word Excitotoxicity.

Definition of Excitotoxicity

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Meaning of Excitotoxicity from wikipedia

- In excitotoxicity, nerve cells suffer damage or death when the levels of otherwise necessary and safe neurotransmitters such as glutamate become pathologically...
- NMDA receptors, causing excessive influx of Ca2+ can lead to excitotoxicity. Excitotoxicity is implied to be involved in some neurodegenerative disorders...
- oxidative stress and excitotoxicity—both of which are highly ****ociated with CNS disorders. Not only can oxidative stress and excitotoxicity trigger neuron...
- Histamine Receptors". "Excitotoxicity and Cell Damage". 2010. M. Aarts; M. Tymianski (2003-09-15). "Novel treatment of excitotoxicity: targeted disruption...
- cascade of excitotoxic cell death and further increased extracellular glutamate concentrations. Glutamate receptors' significance in excitotoxicity also links...
- implicated in excitotoxicity, NMDA receptor antagonists have held much promise for the treatment of conditions that involve excitotoxicity, including benzodiazepine...
- activation of GluA2-containing AMPARs is proposed to guard against excitotoxicity. The subunit composition of the AMPAR is also important for the way...
- kainate receptors. In experiments, it is used to counter glutamate excitotoxicity. NBQX was found to have anticonvulsant activity in rodent seizure models...
- LD50 is also unknown. ODAP activates AMPA receptors which can induce excitotoxicity, or overstimulation of glutamate receptors. The release of too much...
- and consequent excitotoxicity. By blocking extrasynaptic NMDA receptors, nitromemantine is able to largely prevent this excitotoxicity while minimising...