- two-carbon
bridge between carbons 6 and 14 (e.g., 6,14-ethano, or 6,14-
etheno), and
which significantly distorts the C ring, may
increase potency 1,000...
-
bridged oripavine derivatives, due to the
characteristic 6,14-endo-ethano- or
etheno-bridge and
substitution at the 7α position.
Buprenorphine and etorphine...
-
rearrangements in the morphine-thebaine group. II.
Alcohols derived from 6,14-endo-
etheno- and 6,14-endo-ethanotetrahydrothebaine".
Journal of the
American Chemical...
-
studied oxidative DNA
adduct is 8-oxo-dG.
Other adducts known to form are
etheno-, propano-, and malondialdehyde-derived DNA adducts. The
aldehydes formed...
- non-bulky (8-oxoguanine and formamidopyrimidine) and
bulky (cyclopurine and
etheno adducts) base modifications,
abasic sites, non-conventional single-strand...
-
rearrangements in the morphine-thebaine group. II.
Alcohols derived from 6,14-endo-
etheno- and 6,14-endo-ethanotetrahydrothebaine".
Journal of the
American Chemical...
- take
place as a
mutation of DNA. As a DNA
modification it is
called an
etheno (ε) DNA adduct.
Chloroacetaldehyde and 1,3-bis(2-chloroethyl)-1-nitrosourea...
-
endogenously via
lipid peroxidation and
prostoglandin biosynthesis. They
create etheno adducts formed by
aldehyde which undergo rearrangements to form crosslinks...
-
Analysis of BST-1/CD157
complexed with
ethenoNADP 1isi:
Crystal Structure Analysis of BST-1/CD157
complexed with
ethenoNAD 1isj:
Crystal Structure Analysis...
- 0607377104. PMC 1783386. PMID 17213319. Delaney; et al. (2005). "AlkB
reverses etheno DNA
lesions caused by
lipid oxidation in
vitro and in vivo". Nat. Struct...
