- The
esperamicins are
chromoprotein enediyne antitumor antibiotics of
bacterial origin.
Esperamicin A1 is the most well
studied compound in this class....
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members of the
esperamicin family include esperamicin A1, A1b, A2, A3, A4, B1, B2, and X.
Esperamicin X is an
inactive esperamicin naturally produced...
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acute lymphoblastic leukemia.
Calicheamicin γ1 and the
related enediyne esperamicin are the two of the most
potent antitumor agents known. Calicheamicins...
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enediyne functional analogs :
model frameworks based on
calicheamicin and
esperamicin (2001)
Doctoral advisor Martin Semmelhack Other academic
advisors Rebecca...
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calicheamicin C58H84N12O26
Mannopeptimycin glycopeptide C59H80N4O22S4
esperamicin C59H103N3O18
Niphimycin 12676-71-0 C60
Buckminsterfullerene 99685-96-8...
- Brummond, Kay
Michille (1991).
Synthetic approach to the calicheamicin/
esperamicin bicyclo[7.3.1]tridencenediyne ring core and
sulfones in
organic synthesis...
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molecule by the
following mechanism.
Calicheamicin and the
closely related esperamicin have been used as
anticancer drugs due to
their high
toxicity and specificity...
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Dennis S. Yama****a, ****le. Schulte: "Concise
route to the calichemicin-
esperamicin series: the
crystal structure of an
aglycone prototype", in: J. Am. Chem...
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Jasamplexoside B 147742-01-6 C59H79N15O21S6
linaclotide 851199-59-2 C59H80N4O22S4
esperamicin 99674-26-7 C59H81N11O13
stelladelin A 172617-98-0 C59H82CoN16O15P...
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ringed enediyne antitumor antibiotic agents,
which includes: namenamicin,
esperamicin and, calicheamicin. Due to its high
potency from cytotoxicity, Shishjimicin...
