Definition of Erastin. Meaning of Erastin. Synonyms of Erastin

- Erastin is a small molecule capable of initiating ferroptotic cell death. Erastin binds and activates voltage-dependent anion channels (VDAC) by reversing...
- targets of erastin, though it was later found that the mechanistic target of erastin is the cystine/glutamate transporter system xc−. Erastin inhibits system...
- kill engineered tumor cells, identifying and naming the novel compound erastin. Upon completing his fellowship, Stockwell joined the faculty at Columbia...
- NRF2 degradation. Cells expressing a KEAP1 S104A mutant are resistant to erastin-induced ferroptosis, consistent with higher NRF2 levels upon removal of...
- kinetic isotope effect. The protective effect of D-PUFAs was verified in erastin- and RSL3-induced ferroptosis models, with demonstrated efficacy in various...
- D-PUFAs in preventing ferroptosis has been demonstrated in models induced by erastin and RSL3, and has shown promising results in various disease models, especially...
- and tumor formation: implications for potentiating chemosensitivity by erastin », Cancer Res, (2019) 79, p. 3877-3890 Parks SK., et al., « Lactate and...
- inhibits the function of system Xc-. Synthetic small molecules such as erastin, sulfasalazine, and sorafenib can inhibit system Xc- function and induce...
- Bao Ting (2024-04-16). "Strong Protection by 4-Hydroxyestrone against Erastin-Induced Ferroptotic Cell Death in Estrogen Receptor-Negative Human Breast...