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Eptifibatide (Integrilin,
Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Es****), is an
antiplatelet drug of the
glycoprotein IIb/IIIa...
-
blocking the
receptors of this
channel with high
selectivity and affinity,
Eptifibatide was
modeled after a
component in
southeastern pygmy rattlesnake venom...
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Several GpIIb/IIIa
inhibitors exist:
abciximab (abcixifiban) (ReoPro)
eptifibatide (Integrilin)
tirofiban (Aggrastat)
roxifiban orbofiban Glycoprotein IIb/IIIa...
- gpIIb/IIIa
receptor is a
target of
several drugs including abciximab,
eptifibatide, and tirofiban. Once
platelets are activated,
granules secrete clotting...
- monitoring.
Eptifibatide and
tirofiban are anti-clotting
drugs indicated to
prevent thrombosis in
acute ischemic coronary syndromes.
Eptifibatide is additionally...
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Glycoprotein IIB/IIIA
inhibitors (intravenous use only)
Abciximab (ReoPro)
Eptifibatide (Integrilin)
Tirofiban (Aggrastat)
Irreversible cyclooxygenase inhibitors...
- scenarios,
inhibitors of the
platelet glycoprotein αIIbβ3a
receptor such as
eptifibatide or
tirofiban may be used.
There is
varying evidence on the mortality...
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epipropidine (INN)
epirizole (INN)
epiroprim (INN)
epirubicin (INN)
eptifibatide (INN)
epitiostanol (INN)
epitizide (INN)
Epitol epitumomab cituxetan...
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Ticlopidine Desmopressin Factor VIIa
Thrombopoietin mimetics Abciximab Eptifibatide Tirofiban Others: oprelvekin, romiplostim, eltrombopag,
argatroban Platelet...
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concurrent medications clopidogrel, cefoperazone,
valproic acid, cefotetan,
eptifibatide, tirofiban, and ticlopidine.
Anticoagulants and
thrombolytic medications...
