- and that the
epoxygenases typically form a
mixture of R/S
enantiomers at the
attacked double bond position. Thus, the CYP
epoxygenases which attack AA's...
-
eicosapentaenoic acid (EPA), with
certain cytochrome P450
epoxygenases.
These epoxygenases can
metabolize EPA to as many as 10
epoxides that
differ in...
- conditions. ALOXE3
preferentially metabolizes arachidonic acid to hepoxilins.
Epoxygenases:
these are
cytochrome P450
enzymes which generate nonclassic eicosanoid...
- by the CYP
epoxygenases, some of
which differ in activities; 3) the
diversity of
fatty acid
substrates metabolized by the CYP
epoxygenases some of which...
-
metabolizes important endogenous compounds such as
serotonin and,
owing to its
epoxygenase activity,
various polyunsaturated fatty acids,
converting these fatty...
-
Meyer UA, Visvikis-Siest S (November 2014). "Human
cytochrome P450
epoxygenases:
variability in
expression and role in inflammation-related disorders"...
-
polyunsaturated fatty acids that are made by
various cytochrome P450
epoxygenases. EETs, EDPs, and EEQs have
various effects in
animals including vasodilation...
- 9-oxo-octadecdienoic acid.
Certain cytochrome P450 enzymes, the CYP
epoxygenases,
catalyze oxidation of LA to
epoxide products viz., its 12,13-epoxide...
-
their toxic forms (see
table below for examples). CYP3A4 also
possesses epoxygenase activity in that it
metabolizes arachidonic acid to epoxyeicosatrienoic...
-
epoxyeicosatetraenoic acids (EEQs). CYP
epoxygenases similarly convert various other PUFAs to
epoxides (see
Epoxygenase).
These epoxide metabolites have a...