-
Epoxygenases are a set of membrane-bound, heme-containing
cytochrome P450 (CYP450 or just CYP)
enzymes that
metabolize polyunsaturated fatty acids (PUFAs)...
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metabolizes important endogenous compounds such as
serotonin and,
owing to its
epoxygenase activity,
various polyunsaturated fatty acids,
converting these fatty...
-
metabolism of
xenobiotics in the body.
Cytochrome P4502C8 also
possesses epoxygenase activity, i.e. it
metabolizes long-chain
polyunsaturated fatty acids...
-
cytochrome P450
genes on
chromosome no.10 arm q24. CYP2C19 also
possesses epoxygenase activity: it is one of the prin****l
enzymes responsible for attacking...
- acid (19-HETE) (see 20-Hydroxyeicosatetraenoic acid) but also has
epoxygenase activity in that it
metabolizes docosahexaenoic acid to epoxides, primarily...
-
humans (see
epoxyeicosatrienoic acid,
epoxydocosapentaenoic acid, and
epoxygenase pages).
Vernolic and
coronaric acids are
potentially toxic,
causing multiple...
- a
specific subset of
cytochrome P450 enzymes,
termed cytochrome P450
epoxygenases. They are
nonclassic eicosanoids. EETs are
generally short-lived, being...
-
hydroxyeicosatetraenoic acids (HETEs) and
epoxyeicosatrienoic acids (EETs) by
epoxygenase. The
production of
these derivatives and
their actions in the body are...
- (19-HETE) (see 20-Hydroxyeicosatetraenoic acid). However, it also acts as an
epoxygenase activity to
metabolize docosahexaenoic acid to epoxides,
primarily 19R...
-
eicosapentaenoic acid (EPA), with
certain cytochrome P450
epoxygenases.
These epoxygenases can
metabolize EPA to as many as 10
epoxides that
differ in...
