-
epoxomicin include carfilzomib.
Epoxomicin,
Santa Cruz
Biotechnology Meng, L; Mohan, R; Kwok, BH; Elofsson, M; Sin, N; Crews, CM (1999). "
Epoxomicin,...
- inhibitor. Chemically, it is a
tetrapeptide epoxyketone and an
analog of
epoxomicin. It was
developed by Onyx Pharmaceuticals. The US Food and Drug Administration...
- (ONX-0912),
delanzomib (CEP-18770) have also
started clinical trials.
Epoxomicin is a
naturally occurring selective inhibitor. MG132 is a
synthesized peptide...
-
Crews lab's
synthesis and mode of
action studies of the
natural product epoxomicin revealed that it is a
potent and
selective proteasome inhibitor. Subsequent...
- the
natural product epothilone B and
carfilzomib which is
derived from
epoxomicin and
eravacycline derived from tetracycline.
Cabergoline is
derived from...
- sarcomeres, an
effect that was
remedied upon
proteasome inhibition via
epoxomicin. A
missense mutation in ANKRD1 was
shown to be ****ociated with the congenital...