- An
epitope, also
known as
antigenic determinant, is the part of an
antigen that is
recognized by the
immune system,
specifically by antibodies, B cells...
-
Epitope binning is a
competitive immuno****ay used to
characterize and then sort a
library of
monoclonal antibodies against a
target protein. Antibodies...
- In immunology,
cryptic self
epitopes are a
source of autoimmunity. Self
epitopes,
which are
found in high
concentration on the
surface of antigen-presenting...
- In immunology,
epitope mapping is the
process of
experimentally identifying the
binding site, or
epitope, of an
antibody on its
target antigen (usually...
- In immunology, a
conformational epitope is a
sequence of sub-units (usually
amino acids)
composing an
antigen that come in
direct contact with a receptor...
- In immunology, a
linear epitope (also
sequential epitope) is an
epitope—a
binding site on an antigen—that is
recognized by
antibodies by its
linear sequence...
-
antibody recognizes on an
antigen is
called an
epitope.
Several antibodies can
recognize the same
epitope but
differ in
their binding affinity. The antibody...
-
constitutes an
epitope. Most
antigens have the
potential to be
bound by
multiple antibodies, each of
which is
specific to one of the antigen's
epitopes. Using...
- self-tolerance.
Epitope spreading or
epitope drift – when the
immune reaction changes from
targeting the
primary epitope to also
targeting other epitopes. In contrast...
- the same
epitope (the part of an
antigen that is
recognized by the antibody). In contrast,
polyclonal antibodies bind to
multiple epitopes and are usually...
