-
consequences for evolution, are:
rates of
epimutation can be much
faster than
rates of
mutation the
epimutations are more
easily reversible In plants, heritable...
- of
these ac****ulated DNA
damages may give rise to
epimutations.
These new
mutations or
epimutations may
provide a
proliferative advantage, generating...
- divisions, last for
multiple cell generations, and can be
considered to be
epimutations (equivalent to mutations).
While large numbers of
epigenetic alterations...
- expression.
Cancers usually arise from an ****emblage of
mutations and
epimutations that
confer a
selective advantage leading to
clonal expansion (see Field...
-
Somatic evolution is the ac****ulation of
mutations and
epimutations in
somatic cells (the
cells of a body, as
opposed to germ
plasm and stem cells) during...
- of this ac****ulated DNA
damage may give rise to
epimutations.
These new
mutations and/or
epimutations may
provide a
proliferative advantage, generating...
-
describe the
epigenetic alteration(s) and the cancer(s) in
which these epimutations are found. Two
broad experimental survey articles also do****ent most...
-
changes (or "
epimutations") on both the alleles,
rather than
involving any
genetic mutation. In all 19
informative cases, the
epimutations that, together...
-
damages may give rise to
epigenetic alterations or
epimutations.
While a
mutation or
epimutation in a DNA
repair gene, itself,
would not
confer a selective...
-
alterations of the DNA),
mutations (changes in the DNA sequence), and
epimutations (methylation of gene
promoter regions or
alterations of the DNA scaffolding...
