-
consequences for evolution, are:
rates of
epimutation can be much
faster than
rates of
mutation the
epimutations are more
easily reversible In plants, heritable...
-
damages may give rise to
epigenetic alterations or
epimutations.
While a
mutation or
epimutation in a DNA
repair gene, itself,
would not
confer a selective...
-
Somatic evolution is the ac****ulation of
mutations and
epimutations in
somatic cells (the
cells of a body, as
opposed to germ
plasm and stem cells) during...
- of
these ac****ulated DNA
damages may give rise to
epimutations.
These new
mutations or
epimutations may
provide a
proliferative advantage, generating...
-
level (5th level) and
causes increased frequencies of
mutation and/or
epimutation (6th level).
Mutation rates increase substantially in
cells defective...
- of carcinogenesis, the
somatic mutation theory,
mutations in DNA and
epimutations that lead to
cancer disrupt these orderly processes by
interfering with...
- cell
division are damaged.
Carcinogenesis is
caused by
mutation and
epimutation of the
genetic material of
normal cells,
which upsets the
normal balance...
-
alterations of the DNA),
mutations (changes in the DNA sequence), and
epimutations (methylation of gene
promoter regions or
alterations of the DNA scaffolding...
- divisions, last for
multiple cell generations, and can be
considered to be
epimutations (equivalent to mutations).
While large numbers of
epigenetic alterations...
- loss (without replacement), DNA damage,
oncogenic nuclear mutations and
epimutations, cell senescence,
mitochondrial mutations,
lysosomal aggregates, extracellular...
