- In stereochemistry, an
epimer is one of a pair of diastereomers. The two
epimers have
opposite configuration at only one
stereogenic center out of at least...
- the two
activities have been
found in
heparin and some
species of HS.
Epimerisation is
catalysed by one enzyme, the GlcA C5
epimerase or heparosan-N-sulfate-glucuronate...
-
enantiomers do not
racemize readily. All
three stereoisomers undergo epimerisation in the
presence of
organic and
inorganic bases in solution. Lactide...
- oxidation). In some cases, the use of
triethylamine as the base can lead to
epimerisation at the
carbon alpha to the
newly formed carbonyl.
Using a
bulkier base...
-
tertiary stereogenic C5 and C8 positions,
rendering these centers prone to
epimerisation. The C8
proton is more
labile due to the electron-withdrawing carboxamide...
- a
moderate (40 to 90 °C (104 to 194 °F))
heating for a few minutes.
Epimerisation may happen.
Phloroglucinolysis can be used for
instance for proanthocyanidins...
- 5-****topiperazines is
based on the use of
sodium hydride as base.
However epimerisation can
occur especially with proline-fused 2,5-****topiperazines, even...
- water. They
involve a
moderate (50 to 90 °C)
heating for a few minutes.
Epimerisation may happen.
Phloroglucinolysis can be used for
instance for proanthocyanidins...
- van
Ekenstein transformation and
related reactions, in: Glycoscience:
epimerisation,
isomerisation and
rearrangement reactions of carbohydrates, Vol. 215...
- ISBN 978-3-527-61710-4. Stütz,
Arnold E., ed. (2001).
Glycoscience Epimerisation,
Isomerisation and
Rearrangement Reactions of Carbohydrates. Berlin...
