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Epithelial cell
adhesion molecule (
EpCAM), also
known as CD326
among other names, is a
transmembrane glycoprotein mediating Ca2+-independent homotypic...
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EpCAM. It was
developed by
Fresenius Biotech and
Trion Pharma (Germany). The drug is used for the
treatment of
malignant ascites in
people with
EpCAM-positive...
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levels of
EpCAM-positive cells.
Patients with
severe skin
burns can also
carry EpCAM positive cells in the blood. Therefore, the use of
EpCAM-positive...
- aid in the
diagnosis of
basal cell
carcinoma (BCC). It is an
antibody to
EpCAM (epithelial cell
adhesion molecule). BerEp4 has a high
sensitivity and specificity...
- use in the
European Union in June 2022.
Solitomab links T
cells with the
EpCAM antigen which is
expressed by colon, gastric, prostate, ovarian, lung, and...
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idiopathic arthritis,
hemolytic disease of the
newborn Adecatumumab mab
human EpCAM prostate and
breast cancer Aducanumab Aduhelm mab
human Amyloid beta Y Alzheimer's...
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molecule (
EpCAM) on
chromosome 2 (2p21) and SPINT2 on
chromosome 19. SPINT2 is a Kunitz-type
protease inhibitor. The
mutation in the
EpCAM gene in Kuwait...
- One of the
scFvs binds to T
cells via the CD3 receptor, and the
other to
EpCAM as a
tumor antigen against gastrointestinal, lung, and
other cancers. Like...
- DNA
mutation in one of the MMR
genes (MLH1, MSH2, MSH6, and PMS2) or the
EPCAM gene,
identified by
genetic testing.
Candidates for
germline genetic testing...
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interacts with E-cadherin and actin, as well as the cell
adhesion molecule EpCam in the EVL,
which may
modulate adhesion with the
underlying deep cells....
