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Endothelin receptor type
B, (ET-
B) is a
protein that in
humans is
encoded by the
EDNRB gene.
Endothelin receptor type
B is a G protein-coupled receptor...
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There are at
least four
known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of
which are G protein-coupled
receptors whose activation result in elevation...
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endothelin A (ETA) and
B receptors (ETB) aprocitentan, bosentan, macitentan,
tezosentan Selective ETA
Receptor Antagonists,
which affect endothelin A...
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Endothelins are
peptides with
receptors and
effects in many body organs.
Endothelin constricts blood vessels and
raises blood pressure. The endothelins...
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Endothelin receptor type A, also
known as ETA, is a
human G protein-coupled
receptor.
Endothelin receptor type A has been
shown to
interact with HDAC7A...
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subsequently to
mature endothelin,
which the
cells release.
Patients with salt-sensitive
hypertension have
higher plasma ET-1.
Endothelin-1
receptor antagonists...
- protein. The
active peptide is a
ligand for
endothelin receptor type
B (EDNRB). The
interaction of this
endothelin with
EDNRB is
essential for development...
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brand name Tyvalzi) is a
synthetic analog of
endothelin-1 that
works as a
selective endothelin-
B receptor agonist. In May 2023, it was
approved in India...
- Hirschsprung's
disease in humans. A
mutation in the
middle of the
endothelin receptor type
B (EDNRB) gene
causes lethal white syndrome when homozygous. Carriers...
- is
taken by mouth.
Aprocitentan is a
receptor antagonist that
targets both
endothelin A and
endothelin B receptors.
Aprocitentan was
approved for medical...