-
Endothelin receptor type
B, (ET-
B) is a
protein that in
humans is
encoded by the
EDNRB gene.
Endothelin receptor type
B is a G protein-coupled receptor...
-
There are at
least four
known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of
which are G protein-coupled
receptors whose activation result in elevation...
-
endothelin A (ETA) and
B receptors (ETB) aprocitentan, bosentan, macitentan,
tezosentan Selective ETA
Receptor Antagonists,
which affect endothelin A...
-
Endothelin receptor type A, also
known as ETA, is a
human G protein-coupled
receptor.
Endothelin receptor type A has been
shown to
interact with HDAC7A...
-
Endothelins are
peptides with
receptors and
effects in many body organs.
Endothelin constricts blood vessels and
raises blood pressure. The endothelins...
-
subsequently to
mature endothelin,
which the
cells release.
Patients with salt-sensitive
hypertension have
higher plasma ET-1.
Endothelin-1
receptor antagonists...
-
sensorineural deafness. The
syndrome is
caused by
mutation in the
endothelin B receptor gene (EDNRB). In the beginning,
medical officials defined ABCD syndrome...
- Hirschsprung's
disease in humans. A
mutation in the
middle of the
endothelin receptor type
B (EDNRB) gene
causes lethal white syndrome when homozygous. Carriers...
- is
taken by mouth.
Aprocitentan is a
receptor antagonist that
targets both
endothelin A and
endothelin B receptors.
Aprocitentan was
approved for medical...
- to two
different G-protein
coupled receptors (GPCRs), the
endothelin A
receptor (EDNRA) and the
endothelin B receptor (EDNRB). As ET-2 has a very similar...
