- In
molecular biology,
endonucleases are
enzymes that
cleave the
phosphodiester bond
within a
polynucleotide chain (namely DNA or RNA). Some, such as deoxyribonuclease...
- A
restriction enzyme,
restriction endonuclease, REase,
ENase or
restrictase is an
enzyme that
cleaves DNA into
fragments at or near
specific recognition...
- Apurinic/apyrimidinic (AP)
endonuclease is an
enzyme that is
involved in the DNA base
excision repair pathway (BER). Its main role in the
repair of damaged...
-
called sticky ends: 5'-A |A G C T T-3' 3'-T T C G A| A-5'
Restriction endonucleases are used as
defense mechanisms in
prokaryotic organisms in the restriction...
- Flap
endonuclease 1 is an
enzyme that in
humans is
encoded by the FEN1 gene. The
protein encoded by this gene
removes 5'
overhanging "flaps" (or short...
- Flap
endonucleases (FENs, also
known as 5'
durgs in
older references) are a
class of
nucleolytic enzymes that act as both 5'-3'
exonucleases and structure-specific...
-
inappropriate bases,
forming AP sites.
These are then
cleaved by an AP
endonuclease. The
resulting single-strand
break can then be
processed by
either short-patch...
-
displaces the RNA/DNA
initiator primer into a 5′ flap. The FEN1 5’-3’
endonuclease recognizes that the 5’ flap is displaced, and it cleaves,
creating a...
- The
homing endonucleases are a
collection of
endonucleases encoded either as
freestanding genes within introns, as
fusions with host proteins, or as self-splicing...
-
Endonuclease G,
mitochondrial is an
enzyme that in
humans is
encoded by the
ENDOG gene. This
protein primarily parti****tes in caspase-independent apoptosis...
