- An
enamine is an
unsaturated compound derived by the
condensation of an
aldehyde or
ketone with a
secondary amine.
Enamines are
versatile intermediates...
- The
Stork enamine alkylation involves the
addition of an
enamine to a
Michael acceptor (e.g., an α,β -unsaturated
carbonyl compound) or
another electrophilic...
- pattern. Non-carbon
nucleophiles such as water, alcohols, amines, and
enamines can also
react with an α,β-unsaturated
carbonyl in a 1,4-addition. Some...
-
colorless liquid. It is
classified as an
enamine.
Primary and
secondary enamines tend to isomerize, but
tertiary enamines are
kinetically stable. One unusual...
- reactions. In 1963, G.
Stork reported the
first enamine alkylation reaction for
ketones -
Stork enamine alkylation reaction. In 1976,
Meyers reported the...
-
aldehydes toward nucleophilic addition by
formation of
enamines (e.g. used in the
Stork enamine alkylation):
International Union of Pure and
Applied Chemistry...
-
ammonia or a
primary amine gives an
imine With
secondary amine gives an
enamine With
Grignard and
organolithium reagents to give,
after aqueous workup...
-
bonded are far more common.
Isothiazones are
produced by
oxidation of
enamine-thiones. The ring
structure of
isothiazole is
incorporated into larger...
- is
widely used to
convert ketones to
enamines.
Enamines derived from
piperidine are
substrates in the
Stork enamine alkylation reaction. Upon treatment...
-
varying proportions. The
active species is the hexafluoropropylamine; any
enamine is
converted into this by the
hydrogen fluoride byproduct as the reaction...
