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Elexacaftor/tezacaftor/ivacaftor, sold
under the
brand names Trikafta and Kaftrio, is a fixed-dose
combination medication used to
treat cystic fibrosis...
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Elexacaftor is a
medication that acts as
cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It is
available in a
single pill with ivacaftor...
- the
European Union in
October 2018. The
combination of
tezacaftor with
elexacaftor and
ivacaftor (brand name Trikafta) was
approved for
medical use in the...
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combination medications, lumacaftor/ivacaftor, tezacaftor/ivacaftor, and
elexacaftor/tezacaftor/ivacaftor
which are used to
treat people with
cystic fibrosis...
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treat people with the F508del mutation. In 2019, the
combination drug
elexacaftor/ivacaftor/tezacaftor,
marketed as Trikafta,was
approved for CF patients...
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Pembrolizumab Merck endometrial carcinoma Lenvatinib Eisai endometrial carcinoma Elexacaftor/tezacaftor/ivacaftor
Vertex Pharmaceuticals cystic fibrosis Zanubrutinib...
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lumacaftor R07AX31
Ivacaftor and
tezacaftor R07AX32 Ivacaftor,
tezacaftor and
elexacaftor R07AX33 Deutivacaftor,
tezacaftor and
vanzacaftor "ATC (Anatomical Therapeutic...
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filed with it, the FDA
approved Vertex's Triple-combo
therapy Trikafta (
elexacaftor/tezacaftor/ivacaftor) for
patients 12 and
older with at
least one F508del...
- are
approved drugs that
contain the
acylsulfonamide functional group:
Elexacaftor Grazoprevir Parecoxib Selexipag Simeprevir Sulfacetamide Sulfadicramide...
- some
approved CFTR
modulators for
specific mutations. One such drug is
elexacaftor/tezacaftor/ivacaftor. However, the cost of CFTR
modulators is high. In...