- An
ectodomain is the
domain of a
membrane protein that
extends into the
extracellular space (the
space outside a cell).
Ectodomains are
usually the parts...
-
their ligands, Notch-1 and Tie-1
undergo proteolytic cleavage of the
ectodomains by ADAM17 and ADAM10. This
cleavage frees the
cytoplasmic fragment for...
-
glycoproteins with
typically small ectodomains of 6 to 10 nm. NTRs have
either an N-terminal or C
terminal ectodomains.
Ectodomains have a high
sequence diversity...
-
forms a
layer 7.8 nm thick. It has
three domains, a
short N-terminal
ectodomain, a triple-spanning
transmembrane domain, and a C-terminal endodomain....
-
Spike proteins are
membrane proteins with
typically large external ectodomains, a
single transmembrane domain that
anchors the
protein in the viral...
- "Structure of follicle-stimulating
hormone in
complex with the
entire ectodomain of its receptor".
Proceedings of the
National Academy of
Sciences of the...
-
relatively long Thr-Ser-Pro-rich area in the
middle of syndecan- 3's
ectodomain. The
ectodomains show the
least amount of
amino acid
sequence conservation, not...
-
comprising a
short cytoplasmic domain, a
transmembrane segment, and an
ectodomain consisting of a ~100 kDa
fibronectin type III (FNIII) domain. FNDC5 was...
-
membrane proteins, each with
three main regions: an N-terminal
extracellular ectodomain (residues 23–182 in CD8A and 23–170 in CD8B), a
single transmembrane helix...
-
Recent evidence suggests that some such
proteins are
first processed to
ectodomains by
alpha secretases and
subsequently cleaved by
another Alzheimer's-****ociated...
