- An
ectodomain is the
domain of a
membrane protein that
extends into the
extracellular space (the
space outside a cell).
Ectodomains are
usually the parts...
-
their ligands, Notch-1 and Tie-1
undergo proteolytic cleavage of the
ectodomains by ADAM17 and ADAM10. This
cleavage frees the
cytoplasmic fragment for...
-
forms a
layer 7.8 nm thick. It has
three domains, a
short N-terminal
ectodomain, a triple-spanning
transmembrane domain, and a C-terminal endodomain....
-
glycoproteins with
typically small ectodomains of 6 to 10 nm. NTRs have
either an N-terminal or C
terminal ectodomains.
Ectodomains have a high
sequence diversity...
- The large,
uninterrupted N-terminal
exons each
encode six
cadherin ectodomains while the C-terminal
exons encode the
cytoplasmic domain.
These neural...
-
Spike proteins are
membrane proteins with
typically large external ectodomains, a
single transmembrane domain that
anchors the
protein in the viral...
-
regulation of interleukin-6
production positive regulation of
membrane protein ectodomain proteolysis positive regulation of
humoral immune response mediated by...
-
extracellular portions of
transmembrane proteins,
releasing the
soluble ectodomains from the cell surface. Many
sheddases are
members of the ADAM or aspartic...
- C, V and W.
There are two
envelope glycoproteins. The G
glycoprotein ectodomain ****embles as a
homotetramer to form the
viral anti-receptor or attachment...
-
dimer by two
disulphide links extending from each α-chain. The
overall 3D
ectodomain structure,
possessing four
ligand binding sites,
resembles an inverted...
