- An
ectodomain is the
domain of a
membrane protein that
extends into the
extracellular space (the
space outside a cell).
Ectodomains are
usually the parts...
- parti****te in a wide
variety of cell
surface remodeling processes,
including ectodomain shedding,
regulation of
growth factor availability and
mediating cell-matrix...
- Gp41 is a
transmembrane protein that
contains several sites within its
ectodomain that are
required for
infection of host cells. As a
result of its importance...
-
forms a
layer 7.8 nm thick. It has
three domains, a
short N-terminal
ectodomain, a triple-spanning
transmembrane domain, and a C-terminal endodomain....
-
dimer by two
disulphide links extending from each α-chain. The
overall 3D
ectodomain structure,
possessing four
ligand binding sites,
resembles an inverted...
- form is the
transmembrane protein. A
soluble form,
referred to as
either ectodomain or LAD-1, is
generated by
proteolytic processing of the full
length form...
- CNS. SORL1 is a
multi domain single-p****
membrane protein whose large ectodomain resides primarily in
endosomal tubules,
being connected by its transmembrane...
- is
roughly 60 kDA in size. This
cleaving process is
called “receptor
ectodomain shedding. In
humans and rabbits, tumor-necrosis
factor alpha converting...
-
membrane proteins, each with
three main regions: an N-terminal
extracellular ectodomain (residues 23–182 in CD8A and 23–170 in CD8B), a
single transmembrane helix...
- PMID 25824603.
Joutel A,
Andreux F,
Gaulis S, et al. (March 2000). "The
ectodomain of the Notch3
receptor ac****ulates
within the
cerebrovasculature of CADASIL...
