- An
ectodomain is the
domain of a
membrane protein that
extends into the
extracellular space (the
space outside a cell).
Ectodomains are
usually the parts...
- parti****te in a wide
variety of cell
surface remodeling processes,
including ectodomain shedding,
regulation of
growth factor availability and
mediating cell-matrix...
- CNS. SORL1 is a
multi domain single-p****
membrane protein whose large ectodomain resides primarily in
endosomal tubules,
being connected by its transmembrane...
-
dimer by two
disulphide links extending from each α-chain. The
overall 3D
ectodomain structure,
possessing four
ligand binding sites,
resembles an inverted...
-
regulation of interleukin-6
production positive regulation of
membrane protein ectodomain proteolysis positive regulation of
humoral immune response mediated by...
- PMID 25824603.
Joutel A,
Andreux F,
Gaulis S, et al. (March 2000). "The
ectodomain of the Notch3
receptor ac****ulates
within the
cerebrovasculature of CADASIL...
-
Ribbon representation of a
repeating unit in the
extracellular E-cadherin
ectodomain of the
mouse (PDB: 3Q2V)
Identifiers Symbol Cadherin Pfam PF00028 InterPro...
- is
roughly 60 kDA in size. This
cleaving process is
called “receptor
ectodomain shedding. In
humans and rabbits, tumor-necrosis
factor alpha converting...
-
forms a
layer 7.8 nm thick. It has
three domains, a
short N-terminal
ectodomain, a triple-spanning
transmembrane domain, and a C-terminal endodomain....
-
Takao (2011-09-30). "Cytotrienin A, a
translation inhibitor that
induces ectodomain shedding of TNF
receptor 1 via
activation of ERK and p38 MAP kinase"....
