Definition of Druglikeness. Meaning of Druglikeness. Synonyms of Druglikeness

- Druglikeness is a qualitative concept used in drug design for how "druglike" a substance is with respect to factors like bioavailability. It is estimated...
- five or simply the rule of five (RO5), is a rule of thumb to evaluate druglikeness or determine if a chemical compound with a certain pharmacological or...
- Furthermore, newly invented pharmacologically active moieties may have poor druglikeness and may require chemical modification to become drug-like enough to be...
- and hepatic enzymes. In drug design, drug candidates may have good druglikeness but fail on first-p**** metabolism because it is biochemically selective...
- and logistic advantages for physicians and the military. Pharmacology Druglikeness Lipinski's rule of five Metabolite Chemogenomics Neurotransmitter Peptidomimetic...
- chemists in pre-clinical drug discovery, for example, in the ****essment of druglikeness of drug candidates. Likewise, it is used to calculate lipophilic efficiency...
- S2CID 201716327. Gregory, Barber. "A Molecule Designed By AI Exhibits 'Druglike' Qualities". Wired. Archived from the original on 2020-04-30. Retrieved...
- selectivity versus other targets significant efficacy in a cellular ****ay druglikeness (moderate molecular weight and lipophilicity usually estimated as ClogP)...
- Following his release from prison, in 2022, a planned software platform named Druglike controlled by Shkreli was announced with a stated aim of supporting the...
- "First-Principles Calculation of the Intrinsic Aqueous Solubility of Crystalline Druglike Molecules". Journal of Chemical Theory and Com****tion. 8 (9): 3322–3337...