-
occurring in
marine s****-less
mollusc Dolabella auricularia called dolastatins which show
potent activity in
preclinical studies, both in
vitro and...
-
peptides of
dolastatins 10 and 15
noncompetitively inhibit the
binding of
vincristine to tubulin.
Dolastatin 10 is 9
times more
potent than
dolastatin 15 and...
- (ADF/cofilin)
Dystonins Diaphanous Dystroglycan DNase I
Dystrophin Doliculide Dolastatins EAST
Endossin EF-1a (ABP50) Eps15 EF-1b
EPLIN EF-2
Epsin EGF receptor...
-
distraction –
disulfiram – DJ-927 – DNA –
docetaxel – dock –
dolasetron –
dolastatin 10 –
donepezil – dose – dose-dense
chemotherapy – dose-dependent – dose-limiting...
- (1998-10-01). "Isolation,
Structure Determination, and
Biological Activity of
Dolastatin 12 and
Lyngbyastatin 1 from
Lyngbya majuscula/Schizothrix
calcicola Cyanobacterial...
-
group discovered multiple anti-cancer compounds,
including bryostatins,
dolastatins/auristatins, and combretastatins,
several of
which advanced into preclinical...
-
oncological research. It is
structurally analogous to
belamide A and
dolastatin 15. Its
appearance is that of a powdery, white, substance. The N-terminus...
-
isolated from sea squirts.
Monomethyl auristatin E is a
derivative of a
dolastatin 10, a
compound made by
Dolabella auricularia.
Bryostatins were
first isolated...
- Luesch, RE Moore, VJ Paul, SL Mooberry, TH Corbett. 2001.
Isolation of
Dolastatin 10 from the
Marine Cyanobacterium Symploca Species VP642 and
Total Stereochemistry...
