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Dizocilpine (INN), also
known as MK-801, is a pore
blocker of the NMDA receptor, a
glutamate receptor,
discovered by a team at
Merck in 1982. Glutamate...
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dizocilpine site
antagonist Dexanabinol –
dizocilpine-related site
antagonist Diethyl ether –
unknown site
antagonist Diphenidine –
dizocilpine site...
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workers had
recently begun proposing to use NMDA
antagonists PCP, MK-801 (
dizocilpine) and
ketamine in
clinical trials for
various psychological effects; but...
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antagonists include ketamine, tiletamine, dextromethorphan,
nitrous oxide, and
dizocilpine (MK-801).
Research also
indicates that PCP
inhibits nicotinic acetylcholine...
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Ibotenic neurotoxicity can be
enhanced by
glycine and
blocked by
dizocilpine.
Dizocilpine acts as an
uncompetitive antagonist at NMDA receptors. Ibotenic...
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inhibition of
hyperlocomotion induced by the NMDA
receptor antagonist dizocilpine (MK-801) or the
dopamine releasing agent methamphetamine, inhibition...
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Diclofensine Didesmethylsibutramine (BTS-54505)
Dimethocaine Diphenylpyraline Dizocilpine (MK-801) DOV-102,677 DOV-216,303
Efavirenz Ephenidine Esketamine EXP-561...
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selective and high-affinity NMDA
receptor antagonist,
specifically of the
dizocilpine (MK-801) site (Ki = 257 nM). It
produces ketamine-like effects. In addition...
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Others 2-EMSB 2-MDP 8A-PDHQ
Aptiganel Budipine Delucemine Dexoxadrol Dizocilpine Etoxadrol Herkinorin Ibogaine Midafotel NEFA
Neramexane Nitrous oxide...
- receptor. The S-(+) and R-(–)
stereoisomers of
ketamine bind to the
dizocilpine site of the NMDA
receptor with
different affinities, the
former showing...
