- 3-dipolar
cycloaddition is a
chemical reaction between a 1,3-dipole and a
dipolarophile to form a five-membered ring. The
earliest 1,3-dipolar cycloadditions...
- dipole) and the
dipolarophile. When R' is an electron-donating group, alkyl, or aryl, the
dominant FMOs are the HOMO of the
dipolarophile and the LUMO of...
- iminiums. They are
often generated in situ, and
immediately reacted with
dipolarophiles. The
resonance structures below show the 1,3-dipole contribution, in...
-
standard 1,3-cycloaddition
between an
azide 1,3-dipole and an
alkene as
dipolarophile has
largely been
ignored due to lack of
reactivity as a
result of electron-poor...
-
Synthesis of
Isoxazole Derivatives from
Primary Nitro Compounds and
Dipolarophiles: The Role of the Base".
European Journal of
Organic Chemistry. 2006...
-
reaction using a
nitrile oxide as a 1,3-dipole and a
norbornene as a
dipolarophile. Its
primary use has been in
labeling DNA and RNA in
automated oligonucleotide...
- reaction)
between a 1,3-dipole
diazo compound (notably diazomethane) and a
dipolarophile. When the
dipolarphile is an alkene, the
reaction product is a pyrazoline...
- with
triphenylphosphine to an
intermediate zwitterionic allenolate, a
dipolarophile for the 1,3-dipole 2-phenylnitrone. The
primary regioselective [3+2]dipolar...
- ring-opening reaction.
These ylides can be
trapped with a
suitable dipolarophile in a 1,3-dipolar cycloaddition. When the N-substituent is an electron-withdrawing...
-
reaction of the
nitrile ylides is the 1,3-dipolar
cycloaddition to
dipolarophiles: with electron-deficient alkenes, good
yields of
pyrrolines are obtained...
