-
Dimethoxytrityl,
often abbreviated DMT, is a
protecting group widely used for
protection of the 5'-hydroxy
group in nucleosides,
particularly in oligonucleotide...
- 5-triazin-2-yl)-4-methyl-morpholinium chloride) an amide-coupling
reagent Dimethoxytrityl, a
protecting group used in
oligonucleotide synthesis Deadman timer...
- the
presence of a free
secondary 3'-hydroxy
group as a
result of
steric hindrance due to the
dimethoxytrityl group and the
ribose ring (Py = pyridine)....
-
neutral conditions. For instance, half-life of 2-cyanoethyl 5'-O-(4,4'-
dimethoxytrityl)thymidine-3'-O-(N,N-diisopropylamino)phosphite in 95%
aqueous acetonitrile...
-
Removed via
oxidation with DDQ or
ceric ammonium chloride Acetals:
Dimethoxytrityl, [bis-(4-methoxyphenyl)phenylmethyl] (DMT) —
Removed by weak acid....
- reviewed: The 5'-hydroxyl
group is
protected by an acid-labile DMT (4,4'-
dimethoxytrityl) group.
Thymine and uracil,
nucleic bases of
thymidine and uridine...
