- been
implicated in
autophagic induction and ROS production. DL-threo-
Dihydrosphingosine at Sigma-Aldrich.
Retrieved 21
March 2024 from
Millipore Sigma. Schwartz...
- mammals.
These compounds,
specifically known as
phytosphingosine and
dihydrosphingosine (also
known as sphinganine,
although this term is less common), are...
-
condensation required to
yield dihydrosphingosine.
Dehydrosphingosine is then
reduced by
NADPH to
dihydrosphingosine (sphinganine),
acylated to dihydroceramide...
- rate-limiting step of the pathway. In turn, 3-keto-
dihydrosphingosine is
reduced to
dihydrosphingosine,
which is then
followed by
acylation by the enzyme...
- palmitoyltransferase. The
product of this
reaction is reduced,
yielding dihydrosphingosine. The
dihydrosphingosine undergoes N-acylation
followed by
desaturation to yield...
-
feature is the
presence of
sphingolipids (mainly 2′-hydroxymyristoyl
dihydrosphingosine 1-glucuronic acid, "SGL-1") in the
outer membrane of the cell wall...
- (February 2009). "FTY720
inhibits ceramide synthases and up-regulates
dihydrosphingosine 1-phosphate
formation in
human lung
endothelial cells". The Journal...
- PMID 7949096.
Stoffel W,
LeKim D,
Sticht G (May 1968). "Biosynthesis of
dihydrosphingosine in vitro". Hoppe-Seyler's
Zeitschrift für
Physiologische Chemie. 349...
-
characterization of
ketonic intermediates in the
synthesis of
sphingosine and
dihydrosphingosine by cell-free
extracts of
Hansenula ciferri". J. Biol. Chem. 244 (2):...
- S1P: Palmitoyl-CoA
Serine 3-Ketosphinganine (dehydrosphingosine)
Dihydrosphingosine (sphinganine)
Dihydroceramide Ceramide Sphingosine See also: Receptor/signaling...