-
Dihydropyrimidine dehydrogenase deficiency is an
autosomal recessive metabolic disorder in
which there is
absent or
significantly decreased activity of...
- In enzymology, a
dihydropyrimidine dehydrogenase (NADP+) (EC 1.3.1.2) is an
enzyme that
catalyzes the
chemical reaction 5,6-dihydrouracil + NADP+ ⇌ {\displaystyle...
- contra-indicated in
patients that "have a
known complete absence of
dihydropyrimidine dehydrogenase (DPD) activity". In US, as of 2024,
there is no specific...
- may also
induce more
severe diarrhoea by
means of this synergy. The
dihydropyrimidine dehydrogenase (DPD)
enzyme is
responsible for the
detoxifying metabolism...
- J.; Malley, M. F. (1992). "
Dihydropyrimidine calcium channel blockers. 4.
Basic 3-substituted-4-aryl-1,4-
dihydropyrimidine-5-carboxylic acid esters. Potent...
-
oteracil or uracil.
These agents achieve this by
inhibiting the
enzyme dihydropyrimidine dehydrogenase (uracil/gimeracil) or
orotate phosphoribosyltransferase...
-
Depressive personality disorder,
disorder with
depressive features Dihydropyrimidine dehydrogenase, an
enzyme N,N-diethyl-p-phenylenediamine, a phenylenediamine...
-
Other names in
common use
include dehydrogenase, dihydrouracil,
dihydropyrimidine dehydrogenase,
dihydrothymine dehydrogenase,
pyrimidine reductase...
-
normally administered intravenously to
prevent its
degradation by
dihydropyrimidine dehydrogenase in the gut wall.
Doxifluridine is a fluoropyrimidine...
- 4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofur-2-yl]-5-methyl-1,3-
dihydropyrimidine-2,4-dione
Identifiers CAS
Number 50-89-5 Y 3D
model (JSmol) Interactive...
