Definition of Dihydroorotate. Meaning of Dihydroorotate. Synonyms of Dihydroorotate

Here you will find one or more explanations in English for the word Dihydroorotate. Also in the bottom left of the page several parts of wikipedia pages related to the word Dihydroorotate and, of course, Dihydroorotate synonyms and on the right images related to the word Dihydroorotate.

Definition of Dihydroorotate

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Meaning of Dihydroorotate from wikipedia

- Dihydroorotate dehydrogenase (DHODH) is an enzyme that in humans is encoded by the DHODH gene on chromosome 16. The protein encoded by this gene catalyzes...
- 4,5-Dihydroorotic acid is a derivative of orotic acid which serves as an intermediate in pyrimidine biosynthesis. Lacroute F (March 1968). "Regulation...
- class 2 dihydroorotate dehydrogenases (DHOQO, EC 1.3.5.2) is an enzyme with systematic name (S)-dihydroorotate:quinone oxidoreductase. This enzyme catalyses...
- arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. Rheumatoid arthritis and psoriatic arthritis are the...
- (S)-dihydroorotate + NAD+ ⇌ {\displaystyle \rightleftharpoons } orotate + NADH + H+ Thus, the two substrates of this enzyme are (S)-dihydroorotate and...
- dihydroorotase. The latter is converted to orotate by dihydroorotate oxidase. The net reaction is: (S)-Dihydroorotate + O2 → Orotate + H2O2 Orotate is covalently...
- evaluated to treat Crohn's disease and ulcerative colitis. It is a dihydroorotate dehydrogenase inhibitor. "Vidofludimus calcium - Immunic". AdisInsight...
- The compound is synthesized in the body via a mitochondrial enzyme, dihydroorotate dehydrogenase or a cytoplasmic enzyme of pyrimidine synthesis pathway...
- "F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase". Proceedings of the National Academy of Sciences of the...
- Dihydroorotate dehydrogenase (fumarate) (EC 1.3.98.1, dihydroorotate oxidase, pyr4 (gene)) is an enzyme with systematic name (S)-dihydroorotate:fumarate...