Definition of Dihydroorotate. Meaning of Dihydroorotate. Synonyms of Dihydroorotate

Here you will find one or more explanations in English for the word Dihydroorotate. Also in the bottom left of the page several parts of wikipedia pages related to the word Dihydroorotate and, of course, Dihydroorotate synonyms and on the right images related to the word Dihydroorotate.

Definition of Dihydroorotate

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Meaning of Dihydroorotate from wikipedia

- Dihydroorotate dehydrogenase (DHODH) is an enzyme that in humans is encoded by the DHODH gene on chromosome 16. The protein encoded by this gene catalyzes...
- 4,5-Dihydroorotic acid is a derivative of orotic acid which serves as an intermediate in pyrimidine biosynthesis. Lacroute F (March 1968). "Regulation...
- arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. Rheumatoid arthritis and psoriatic arthritis are the...
- dihydroorotase. The latter is converted to orotate by dihydroorotate oxidase. The net reaction is: (S)-Dihydroorotate + O2 → Orotate + H2O2 Orotate is covalently...
- The compound is synthesized in the body via a mitochondrial enzyme, dihydroorotate dehydrogenase or a cytoplasmic enzyme of pyrimidine synthesis pathway...
- phosphate synthetase II, aspartate carbamoyltransferase and dihydroorotase. Dihydroorotate dehydrogenase (DHODH) unlike CAD and UMPS is a mono-functional enzyme...
- class 2 dihydroorotate dehydrogenases (DHOQO, EC 1.3.5.2) is an enzyme with systematic name (S)-dihydroorotate:quinone oxidoreductase. This enzyme catalyses...
- Dihydroorotate dehydrogenase (fumarate) (EC 1.3.98.1, dihydroorotate oxidase, pyr4 (gene)) is an enzyme with systematic name (S)-dihydroorotate:fumarate...
- drugs and infections are often fatal. Drugs targeting the class II dihydroorotate dehydrogenase (DHODH) proteins of L. prolificans, Scedosporium, Aspergillus...
- a drug that acts as a potent and selective inhibitor of the enzyme dihydroorotate dehydrogenase. It blocks synthesis of pyrimidine based nucleotides in...