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Dihydromorphine (Paramorfan, Paramorphan) is a semi-synthetic
opioid structurally related to and
derived from morphine. The 7,8-double bond in morphine...
- and the
metabolite dihydromorphine is
likewise twice as
strong as morphine.
Dihydrocodeine (DHC) is O-demethylated into
dihydromorphine (DHM) by CYP2D6 and...
-
dihydromorphine, hydromorphinol, and
oxymorphone during the experiments.
Three paths were found: from
morphine to
hydromorphone with
dihydromorphine as...
-
Dihydrin (dihydrocodeine, 1911), and
Dimorphan (
dihydromorphine).
Paramorfan is the
trade name of
dihydromorphine from
another manufacturer, as is Paracodin...
- thebaine, and in some
cases negligible amounts of hydromorphone,
dihydromorphine, dihydrocodeine, tetrahydro-thebaine, and
hydrocodone (these compounds...
-
deacetylation to
produce dihydromorphine.
Since acetyldihydrocodeine has
higher lipophilicity than
codeine and is
converted into
dihydromorphine rather than morphine...
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Dihydrocodeine is
metabolised by the CYP450
system isoenzyme 2D6 to
dihydromorphine,
which mediates the
majority of its
analgesic effects.
Owing to the...
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subsequently further metabolised to
dihydromorphine.
Since the
final active metabolite is the
slightly stronger opiate dihydromorphine rather than morphine, nicodicodine...
-
dihydrocodeine is to codeine. The
metabolites of
nicodicodeine include dihydromorphine where nicocodeine is
turned into
morphine as
noted above. Nicocodeine...
- a
duration of
action of
around 4–7 hours. As an ester/analogue of
dihydromorphine,
diacetyldihydromorphine is
presumably a
Schedule I/Narcotic controlled...
