-
lovastatin are lovB, lovC, lovA, lovD, lovG, and lovF . The
synthesis of
dihydromonacolin L
requires a
total of 9-malonyl Coa . It
proceeds in the PKS pathway...
- H+ + S-adenosyl-L-methionine ⇌ {\displaystyle \rightleftharpoons }
dihydromonacolin L + 9 CoA + 8 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O The...
- L-ornithine N 5-monooxygenase [NAD(P)H] EC 1.14.13.197: Now EC 1.14.14.124,
dihydromonacolin L
hydroxylase EC 1.14.13.198: Now EC 1.14.14.125,
monacolin L hydroxylase...
-
thioesterase EC 3.1.2.30: (3S)-malyl-CoA
thioesterase * EC 3.1.2.31:
dihydromonacolin L-[lovastatin
nonaketide synthase]
thioesterase * EC 3.1.2.32:...
