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Dihydrolipoyl transacetylase (or
dihydrolipoamide acetyltransferase) is an
enzyme component of the
multienzyme pyruvate dehydrogenase complex. The pyruvate...
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directly involved in
decarboxylation of the pyruvate. The E2 subunit, or
dihydrolipoyl acetyltransferase, for both
prokaryotes and eukaryotes, is generally...
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Dihydrolipoamide dehydrogenase (DLD), also
known as
dihydrolipoyl dehydrogenase, mitochondrial, is an
enzyme that in
humans is
encoded by the DLD gene...
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enzyme that
catalyzes the
chemical reaction succinyl-CoA +
enzyme N6-(
dihydrolipoyl)lysine ⇌ {\displaystyle \rightleftharpoons } CoA + enzyme...
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pyrophosphate (TPP) E2 EC 2.3.1.61
dihydrolipoyl succinyltransferase DLST
lipoic acid,
Coenzyme A E3 EC 1.8.1.4
dihydrolipoyl dehydrogenase DLD FAD, NAD...
- 2-methylpropanoyl-CoA +
enzyme N6-(
dihydrolipoyl)lysine ⇌ {\displaystyle \rightleftharpoons } CoA +
enzyme N6-(S-[2-methylpropanoyl]
dihydrolipoyl)lysine Thus, the two...
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multiple copies of 3 enzymes: E1 (PDHA1);
dihydrolipoyl transacetylase (DLAT) (E2; EC 2.3.1.12); and
dihydrolipoyl dehydrogenase (DLD) (E3; EC 1.8.1.4). The...
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metabolism EC 2.3.1.12
dihydrolipoyl transacetylase (E2) DLAT
pyruvate dehydrogenase complex (PDC)
energy metabolism EC 2.3.1.61
dihydrolipoyl succinyltransferase...
- Hu CW, Ku LS,
Markovitz PJ, Cox RP (1985). "Subunit
structure of the
dihydrolipoyl transacylase component of branched-chain alpha-keto acid dehydrogenase...
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Common tethers are
lipoate -lysine
residue complex ****ociated with
dihydrolipoyl transacetylase,
which is used for
carrying hydroxyethyl from hydroxyethyl...
