- fluoride, is a hydrofluoroolefin. This colorless,
flammable gas is a
difluorinated derivative of ethylene.
Global production in 1999 was approximately...
- Baskin, J. M.; Agard, N. J.; Bertozzi, C. R. (2008). "Second-Generation
Difluorinated Cyclooctynes for Copper-Free
Click Chemistry". J. Am. Chem. Soc. 130...
-
titanium catalyzed reaction of
chlorodifluoromethyl ketones leading to α,α-
difluorinated β-hydroxy ketones".
Chemistry Letters. 13 (7): 1165–1168. doi:10.1246/cl...
- with
lithium enolates.
Other metal enolates afforded large amounts of
difluorinated products.
Although the use of
molecular fluorine as an electrophilic...
- "Invention of MK-7845, a SARS-CoV-2 3CL
Protease Inhibitor Employing a
Novel Difluorinated Glutamine Mimic".
Journal of
Medicinal Chemistry. 67 (5): 3935–3958...
- solubility, but it
still had poor kinetics.
Monofluorinated (****) and
difluorinated (DIFO)
cyclooctynes were
created to
increase the rate
through the addition...
- Complex. Chem. Eur. J., 20: 14493–14498. doi:10.1002/chem.201404144
Difluorinated Danishefsky's diene: a
versatile C(4)
building block for the fluorinated...
-
Staudinger ligation.
After OCT and **** (monofluorinated cyclooctyne), the
difluorinated cyclooctyne (DIFO) was developed. An
improved synthetic approach to...
-
Maciej Grzywa (2013-11-15), "Sorption and
breathing properties of
difluorinated MIL-47 and Al-MIL-53 frameworks",
Microporous and
Mesoporous Materials...
-
ketimines by
chiral phosphoric acid-catalyzed Mukaiyama–Mannich reaction.
Difluorinated silyl enol
ethers are
involved to
produce enantioenriched fluoroalkyl-functionalized...