-
Dichlorocarbene is the
reactive intermediate with
chemical formula CCl2.
Although this
chemical species has not been isolated, it is a
common intermediate...
-
heterocycles such as
pyrroles and
indoles are also
known to react.
Dichlorocarbenes can
react with
alkenes and
amines to form
dichlorocyclopropanes and...
-
isocyanide synthesis)
alkali base
reacts with
chloroform to
produce dichlorocarbene. The
carbene then
converts primary amines to isocyanides. Illustrative...
- chloroform, and base. The
conversion involves the
intermediacy of
dichlorocarbene.
Illustrative is the
synthesis of tert-butyl
isocyanide from tert-butylamine...
- and CA = 0.44. As a reagent,
chloroform serves as a
source of the
dichlorocarbene intermediate CCl2. It
reacts with
aqueous sodium hydroxide, usually...
-
Pyrroles can
react with carbenes, such as
dichlorocarbene, in a [2+1]-cycloaddition. With
dichlorocarbene, a
dichlorocyclopropane intermediate is formed...
- Ciamician–Dennstedt
rearrangement entails the ring-expansion of
pyrrole with
dichlorocarbene to 3-chloropyridine. In the Gattermann–Skita synthesis, a malonate...
- behavior, pot****ium tert-butoxide
reacts with
chloroform yielding dichlorocarbene,
which is
useful for dichlorocyclopropanations. Pot****ium tert-butoxide...
-
Typical reactions include benzylation of
amines and
generation of
dichlorocarbene from chloroform. Bu4NOH can be
neutralized with a
variety of mineral...
- (I2),
chlorine (Cl2),
sulfenyl ion (RS+),
mercury cation (Hg2+), and
dichlorocarbene (:CCl2) also
react through similar pathways. The
direct conversion...
