-
Although ATP
synthase in
bacteria is
similar to its
eukaryotic analogue,
diarylquinoline agents (such as TMC207) are very
specific to the
bacterial enzyme,...
- An
antimycobacterial is a type of
medication used to
treat Mycobacteria infections.
Types include:[citation needed]
Tuberculosis treatments Leprostatic...
- found, it has not been well
studied in this po****tion. It is in the
diarylquinoline antimycobacterial class of medications. It
works by
blocking the ability...
-
subunit C InterPro: IPR000454 ATP5G1; ATP5G2; ATP5G3; ATP6V0B; ATP6V0C;
Diarylquinoline Kühlbrandt W,
Davies KM (January 2016). "Rotary ATPases: A New Twist...
- (Removed in 2005)
Risperdal (risperidone)
Sirturo (bedaquiline) – an
diarylquinoline anti-tuberculosis drug,
discovered by Koen
Andries and his team, which...
-
Patent Office.
Andries K, Verh****elt P,
Guillemont J, et al. (2005), A
diarylquinoline drug
active on the ATP-synthase of
Mycobacterium tuberculosis, Science...
-
inhibitor (NNRTI)
Bedaquiline (TMC207/R207910,
tradename Sirturo), an
diarylquinoline anti-tuberculosis drug
Rilpivirine (TMC278,
tradename Edurant), an...
-
bioactive reductive activation.[failed verification]
Bedaquiline is a
diarylquinoline that has a
different mechanism; this drug
directly inhibits energy...