Definition of Diabody. Meaning of Diabody. Synonyms of Diabody

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Definition of Diabody

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Meaning of Diabody from wikipedia

- five amino acids), forcing scFvs to dimerize. This type is known as diabodies. Diabodies have been shown to have dissociation constants up to 40-fold lower...
- "CD19-/CD3-bispecific antibody of the BiTE class is far superior to tandem diabody with respect to redirected tumor cell lysis". Molecular Immunology. 44...
- commonly produced. These are the Fab recombinant antibodies, scFv and diabodies. Each of the formats has a slightly different potential in applications...
- targeting component now include multiple smaller antibody fragments like diabodies, Fab, scFv, and bicyclic peptides. The first generation uses linking technologies...
- ; et al. (2004). "A Single Treatment of Yttrium-90-labeled CHX-A–C6.5 Diabody Inhibits the Growth of Established Human Tumor Xenografts in Immunodeficient...
- targeting of immunotherapeutic drugs to the cancer cell. Anti-CD19/CD16 diabodies have been shown to enhance the natural killer cell response to B-cell...
- Von der Lieth CW, Matys ER, Little M (October 1999). "Bispecific tandem diabody for tumor therapy with improved antigen binding and pharmacokinetics"....
- retrieved 2021-12-08 Holliger, P.; Prospero, T.; Winter, G. (1993-07-15). ""Diabodies": small bivalent and bispecific antibody fragments". Proceedings of the...
- Holliger developed a new type of bispecific antibody fragment, called a diabody and worked on elucidating the infection pathway of filamentous bacteriophages...
- molecular weight antibodies and resulted in the development of minibodies, diabodies, single chain variable fragments (scFv) and single domain fragments (Fv)...