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Deubiquitinating enzymes (DUBs), also
known as
deubiquitinating peptidases,
deubiquitinating isopeptidases, deubiquitinases,
ubiquitin proteases, ubiquitin...
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hydrolase L1 (EC 3.1.2.15,
ubiquitin C-terminal hydrolase, UCH-L1) is a
deubiquitinating enzyme. UCH-L1 is a
member of a gene
family whose products hydrolyze...
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protein 20 and VHL protein-interacting
deubiquitinating enzyme 2 (VDU2), is a
cysteine protease deubiquitinating enzyme (DUB). The
catalytic site of USP20...
- Ubiquitin-AMC is a
fluorogenic substrate for a wide
range of
deubiquitinating enzymes (DUBs),
including ubiquitin C-terminal
hydrolases (UCHs) and ubiquitin...
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enzyme that in
humans is
encoded by the USP16 gene. This gene
encodes a
deubiquitinating enzyme that is
phosphorylated at the
onset of
mitosis and then dephosphorylated...
- (CDC34) R2 S V1 V2 Z E3
Ubiquitin ligase VHL
Cullin CBL MDM2
FANCL UBR1
Deubiquitinating enzyme:
Ataxin 3 USP6 CYLD ATG3 BIRC6 UFC1 Ubiquitin-like proteins...
- ubiquitin-specific
processing (UBP)
family of
proteases that is a
deubiquitinating enzyme (DUB) with His and Cys domains. This
protein is
located in the...
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stabilized in
response to
oncogenic insults. USP42 has also been
shown to
deubiquitinate p53 and may be
required for the
ability of p53 to
respond to stress...
- and
degradation of p53. In
response to
oncogenic insults,
HAUSP can
deubiquitinate p53 and
protect p53 from Mdm2-mediated degradation,
indicating that...
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proteases that is a
deubiquitinating enzyme (DUB) with His and Cys domains. This
protein is
located in the
nucleoli and
deubiquitinate nucleophosmin and...