-
known as
deubiquitinating peptidases,
deubiquitinating isopeptidases,
deubiquitinases,
ubiquitin proteases,
ubiquitin hydrolases, or
ubiquitin isopeptidases...
- PMID 36563145. Htet ZM, Dong KC,
Martin A (24
October 2024). "The
deubiquitinase Rpn11
functions as an
allosteric ubiquitin sensor to
promote substrate...
-
inflammatory stimuli also
activate NF-κB-induced
expression of the
deubiquitinase A20 (TNFAIP3),
which has been
shown to
intrinsically repair the endothelial...
- inflammasome,.
Antagonistic to
LUBAC are
deubiquitinases such as
OTULIN or CYLD, of
which OTULIN is the only
deubiquitinase that
removes M1-linked
ubiquitin linkages...
- OTU
deubiquitinase 5 is a
protein that in
humans is
encoded by the OTUD5 gene. This gene
encodes a
member of the OTU (ovarian tumor) domain-containing...
- PMC 6878220. PMID 31085270. Lei H, Wang J, Hu J, Zhu Q, Wu Y (August 2021). "
Deubiquitinases in
hematological malignancies".
Biomarker Research. 9 (1): 66. doi:10...
- proliferation, and
inflammatory response.
Complex I is
negatively regulated by
deubiquitinases such as A20, CYLD, and OTULIN,
which destabilize complex I. Complex...
- for
Western Blot analysis. NEM has also been used as an
inhibitor of
deubiquitinases. N-Ethylmaleimide was used by
Arthur Kornberg and
colleagues to knock...
-
ubiquitin carboxy-terminal
hydrolase (UCH)
domain that
gives BAP1 its
deubiquitinase activity.
Recent studies have
shown that BAP1 and its
fruit fly homolog...
- coronaviruses, can also
cleave isopeptide bonds and can
function as
deubiquitinases. In animals,
especially in
mammalian biology,
members of the papain-like...
