-
known as
deubiquitinating peptidases,
deubiquitinating isopeptidases,
deubiquitinases,
ubiquitin proteases,
ubiquitin hydrolases, or
ubiquitin isopeptidases...
- OTU
deubiquitinase 5 is a
protein that in
humans is
encoded by the OTUD5 gene. This gene
encodes a
member of the OTU (ovarian tumor) domain-containing...
-
inflammatory stimuli also
activate NF-κB-induced
expression of the
deubiquitinase A20 (TNFAIP3),
which has been
shown to
intrinsically repair the endothelial...
-
disulfide bonds. It is also used in
ubiquitin studies as an
inhibitor of
deubiquitinase enzymes (DUBs)
because it
alkylates the
cysteine residues at the DUB...
-
ubiquitin carboxy-terminal
hydrolase (UCH)
domain that
gives BAP1 its
deubiquitinase activity.
Recent studies have
shown that BAP1 and its
fruit fly homolog...
-
medium wave (green-cone)
sensitive opsin OTUD5:
encoding protein OTU
deubiquitinase 5 PASD1:
encoding protein PAS domain-containing
protein 1 PAGE1: encoding...
- OTU
deubiquitinase 1 is a
protein that in
humans is
encoded by the OTUD1 gene.
Deubiquitinating enzymes (DUBs; see MIM 603478) are
proteases that specifically...
- NF-κB signaling. Also the
hypomorphic mutations in
deubiquitinase enzyme OTULIN (from OTU
deubiquitinase with
linear linkage specificity),
results in elevated...
-
terminating endotoxin- and TNF-induced NF-kappa B responses. In brief,
deubiquitinase function of TNFAIP3 was
shown to
remove ubiquitin chains from VE-cadherin...
- proliferation, and
inflammatory response.
Complex I is
negatively regulated by
deubiquitinases such as A20, CYLD, and OTULIN,
which destabilize complex I. Complex...
