- cell
layer formation and
structure formation,
desmosomal cadherins focus on
resisting cell damage.
Desmosomal cadherins maintain the
function of desmosomes...
- ARVC can also
develop in
intense endurance athletes in the
absence of
desmosomal abnormalities. Exercise-induced ARVC is
possibly a
result of excessive...
-
characterization of
desmoplakins I and II, the
major polypeptides of the
desmosomal plaque".
Journal of
Molecular Biology. 163 (4): 647–671. doi:10...
-
spanning approximately 45 kDa of
genomic DNA.
Desmoplakin is a
large desmosomal plaque protein that
homodimerizes and
adopts a dumbbell-shaped conformation...
- via
homophilic and
heterophilic interactions. The
cytoplasmic tails of
desmosomal cadherins bind to
plakoglobin and plakophilins,
which bind desmoplakin...
- The
desmogleins are a
family of
desmosomal cadherins consisting of
proteins DSG1, DSG2, DSG3, and DSG4. They play a role in the
formation of desmosomes...
-
Desmocollins are a
subfamily of
desmosomal cadherins, the
transmembrane constituents of desmosomes. They are co-expressed with
desmogleins to link adjacent...
-
adolescence or adulthood. This
condition is due to
mutations in structural/
desmosomal proteins found within stratified squamous epithelium. Dark dot disease...
- cell
desmosomes and
nuclei and
binds plakoglobin, desmoplakin, and the
desmosomal cadherins via N-terminal head domain.
Plakophilin 2
functions to link...
-
through its
cytoplasmic tail. Desmocollin-2 is
ubiquitously expressed in
desmosomal tissues, such as skin epithelia, and is the only
desmocollin isoform expressed...
