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Desmocollins are a
subfamily of
desmosomal cadherins, the
transmembrane constituents of desmosomes. They are co-expressed with
desmogleins to link adjacent...
- Barry; Shapiro,
Lawrence (2016). "Structural
basis of
adhesive binding by
desmocollins and desmogleins". PNAS. 113 (26): 7160–7165. Bibcode:2016PNAS..113.7160H...
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cardiac muscle.
Desmocollins are
integral components to
desmosomes and
studies have
shown that in
addition to
tensile strength,
desmocollins also function...
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attach cells to the
extracellular matrix.
Instead of
desmogleins and
desmocollins in the
extracellular space,
hemidesmosomes utilize integrins. Hemidesmosomes...
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cadherin superfamily includes cadherins, protocadherins, desmogleins,
desmocollins, and more. In structure, they
share cadherin repeats,
which are the extracellular...
-
Stehr S, et al. (1997). "Patterns of
desmocollin synthesis in
human epithelia:
immunolocalization of
desmocollins 1 and 3 in
special epithelia and in cultured...
- system.
Junctional protein Condition(s)
Desmocollin 1
Subcorneal pustular dermatosis type of IgA
pemphigus Desmocollin 2
Arrhythmogenic right ventricular dysplasia...
-
Stehr S, et al. (1997). "Patterns of
desmocollin synthesis in
human epithelia:
immunolocalization of
desmocollins 1 and 3 in
special epithelia and in cultured...
-
mutations in the
genes encoding the
proteins desmoplakin, plakoglobin,
desmocollin-2, and SRC-interacting
protein (SIP).
Naxos disease has the same cutaneous...
-
classical cadherins, non-classical
cadherins such as
desmogleins and
desmocollins act as
adhesion molecules and they are
linked to
intermediate filaments...
