-
Dermatan sulfate is a
glycosaminoglycan (formerly
called a mucopolysaccharide)
found mostly in skin, but also in
blood vessels,
heart valves, tendons,...
- iduronate-2-sulfatase (I2S). The lack of this
enzyme causes heparan sulfate and
dermatan sulfate to ac****ulate in all body tissues.
Hunter syndrome is the only...
-
disaccharide structures: Heparin/heparan
sulfate (HSGAGs)
Chondroitin sulfate/
dermatan sulfate (CSGAGs)
which along with
HSGAGs are
synthesized in the
Golgi apparatus...
-
Dermatan 4-sulfotransferase (EC 2.8.2.35,
dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase,
dermatan-4-sulfotransferase-1,
dermatan-4-sulfotransferase...
-
chondroitin is a
chondrin derivative.
Types include:
Chondroitin sulfate Dermatan sulfate Chondroitin as a
supplement is now
commonly used (often in combination...
-
responsible for
breaking down GAGs.: 544
Without this enzyme, a
buildup of
dermatan sulfate and
heparan sulfate occurs in the body.
Symptoms appear during...
-
molecules are
bound to a
collagen fibril,
their dermatan sulfate chains may
extend and ****ociate with
other dermatan sulfate chains on
decorin that is
bound to...
- IH
Hurler syndrome 607014 IDUA 4p16.3 α-L-iduronidase
Heparan sulfate Dermatan sulfate Intellectual disability, micrognathia, co****
facial features,...
- gene,
encodes for the
enzyme carbohydrate sulfotransferase 14 (CHST14)/
dermatan 4-O-sulfotransferase (D4ST1). In humans, CHST14 is
positioned on the long...
- (GAGs, also
known as mucopolysaccharides). In particular, ARSB
breaks down
dermatan sulfate and
chondroitin sulfate.
Because people with MPS-VI lack the ability...
