-
Dermatan sulfate is a
glycosaminoglycan (formerly
called a mucopolysaccharide)
found mostly in skin, but also in
blood vessels,
heart valves, tendons,...
-
disaccharide structures: Heparin/heparan
sulfate (HSGAGs)
Chondroitin sulfate/
dermatan sulfate (CSGAGs)
which along with
HSGAGs are
synthesized in the
Golgi apparatus...
- iduronate-2-sulfatase (I2S). The lack of this
enzyme causes heparan sulfate and
dermatan sulfate to ac****ulate in all body tissues.
Hunter syndrome is the only...
-
molecules are
bound to a
collagen fibril,
their dermatan sulfate chains may
extend and ****ociate with
other dermatan sulfate chains on
decorin that is
bound to...
-
chondroitin is a
chondrin derivative.
Types include:
Chondroitin sulfate Dermatan sulfate Chondroitin as a
supplement is now
commonly used (often in combination...
-
responsible for
breaking down GAGs.: 544
Without this enzyme, a
buildup of
dermatan sulfate and
heparan sulfate occurs in the body.
Symptoms appear during...
- (GAGs, also
known as mucopolysaccharides). In particular, ARSB
breaks down
dermatan sulfate and
chondroitin sulfate.
Because people with MPS-VI lack the ability...
-
Dermatan 4-sulfotransferase (EC 2.8.2.35,
dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase,
dermatan-4-sulfotransferase-1,
dermatan-4-sulfotransferase...
- N-sulfated
polysaccharides such as
chondroitin sulfate and
dermatan sulfate,
chondroitin sulfate and
dermatan sulfate not
being susceptible to
nitrous acid cleavage...
- It
catalyses the
hydrolysis of
unsulfated α-L-iduronosidic
linkages in
dermatan sulfate. It is a
glycoprotein enzyme found in the
lysosomes of cells. It...
