Definition of Depurination. Meaning of Depurination. Synonyms of Depurination

- Depurination is a chemical reaction of purine deoxyribonucleosides, deoxyadenosine and deoxyguanosine, and ribonucleosides, adenosine or guanosine, in...
- important in binding elongation factors during protein synthesis. The depurination event rapidly and completely inactivates the ribosome, resulting in toxicity...
- 000 to 10,000 DNA purine bases turn over every day due to hydrolytic depurination, and that this is largely counteracted by specific rapid DNA repair processes...
- high pH (low pH also melts DNA, but since DNA is unstable due to acid depurination, low pH is rarely used). The stability of the dsDNA form depends not...
- be generated in a cell daily. AP sites can be formed by spontaneous depurination, but also occur as intermediates in base excision repair. In this process...
- derivatives that form adducts with DNA. These derivatives can cause depurination, the removal of bases from the phosphodiester backbone of DNA, followed...
- direct exposure to an agent. A few common spontaneous mutations are: Depurination – The loss of a purine (A or G) base to form an apurinic site. An apurinic...
- is an important factor in the spontaneous creation of GC tautomers. Depurination – Loss of a purine base (A or G) to form an apurinic site (AP site)....
- Some adducts may also result in the depurination of the DNA; it is, however, uncertain how significant such depurination as caused by the adducts is in generating...
- alkaline denaturation prior to staining leading to an almost complete depurination of the DNA. After washing the probe the remaining DNA is renatured again...