-
depsipeptide is a
peptide in
which one or more of its amide, -C(O)NHR-,
groups are
replaced by the
corresponding ester, -C(O)OR-. Many
depsipeptides have...
- deacetylases, thus
inducing apoptosis. It is
sometimes referred to as
depsipeptide,
after the
class of
molecules to
which it belongs.
Romidepsin is branded...
- cereulide, this
cyclic ester (or lactone)
linkage makes cereulide a
depsipeptide. CesA is a 387 kDa
heterodimer protein composed of CesA1 and CesA2 modules...
-
Pallasch C,
Weibert G,
Kemkers A,
Hummel M, Re D (February 2009). "
Depsipeptide induces cell
death in
Hodgkin lymphoma-derived cell lines". Leuk. Res...
-
development of
uveal melanoma and its
pharmacological inhibition (cyclic
depsipeptide FR900359 inhibitor),
decreases tumor growth in
preclinical trials. The...
-
Mortensen OV, Osei-Owusu P (2019). "Anti-hypertensive
mechanisms of
cyclic depsipeptide inhibitor ligands for G(q/11)
class G proteins".
Pharmacol Res. 141:...
-
Auristatin E) CD30 and
Microtubules 9/19
Cancer Plitidepsin Aplidin Tunicate Depsipeptide Rac1 and JNK
Activation 1/7
Cancer Phase II
DMXBA (GTS-21) N/A Worm Alkaloid...
-
composed of two or more
monocyclic aromatic units linked by an
ester group Depsipeptide, a type of
ester that is a
peptide in
which one or more of its amide...
-
spectrum of
action to erythromycin.
Pristinamycin IA (streptogramin B) is a
depsipeptide. PI and PII are
coproduced by S.
pristinaespiralis in a
ratio of 30:70...
- 920. Ciufolini, M.A.; Swaminathan, S. (1989). "Synthesis of a
model depsipeptide segment of
Luzopeptins (BBM 928),
potent antitumor and antiretroviral...
