-
trimethyl orthoformate is an acetal. In
general cases,
these acetals can be
deprotected back to the
aldehyde by
using hydrochloric acid.
Trimethyl orthoformate...
- ****embly, the
product is
released from the
solid phase to solution,
deprotected, and collected. The
occurrence of side
reactions sets
practical limits...
- acetals.
These acetals are
resistant to the acid
hydrolysis and can be
deprotected easily by
classical reductive conditions. Chéry, Florence; Rollin, Patrick;...
-
groups such as
carboxybenzyl (Cbz) or
allyloxycarbonyl (alloc) can be
deprotected using 2-mercaptoethanol in the
presence of pot****ium
phosphate in dimethylacetamide...
-
alcohols are esters,
deprotected by nucleophiles;
triorganosilyl ethers,
deprotected by
acids and
fluoride ions; and (hemi)acetals,
deprotected by weak acids...
-
symmetrical Sonogashira coupling with
trimethylsilylacetylene (with the TMSA
deprotected to
acetylene in situ) to form
dimethyl 4,4'-(ethyne-1,2-diyl)dibenzoate...
- para-bromination and
oxidation of the ring
system with DDQ, the
amine was
deprotected yielding (R)-(-)-Bromo-DragonFLY. Bromo-DragonFLY was
first synthesized...
- Me3Si−O and Me3Si−N
groups allow them to be
easily removed afterwards ("
deprotected").
Trimethylsilylation can also be used to
increase the
volatility of...
- The
resulting sulfonamide structure is
extremely stable. It can be
deprotected to
reveal the
amine using reductive or
strongly acidic conditions. Tosyl...
- support, with the N-terminus
extending off it. When that
nitrogen is
deprotected, a
ninhydrin test
yields blue. Amino-acid
residues are
attached with...
