Definition of Demethylation. Meaning of Demethylation. Synonyms of Demethylation

- Demethylation is the chemical process resulting in the removal of a methyl group (CH3) from a molecule. A common way of demethylation is the replacement...
- DNA demethylation causes replacement of 5-methylcytosine (5mC) in a DNA sequence by cytosine (C) (see figure of 5mC and C). DNA demethylation can occur...
- mouse, demethylation of DNA, particularly at sites of methylated cytosines, is likely a key process in establishing totipotency. Demethylation involves...
- modification involving methylated cytosine is its demethylation by TET enzymes. Hundreds of such demethylations occur, for instance, during learning and memory...
- hepatic portal vein results in some of the drug being metabolized by O-demethylation into an active metabolite of dextromethorphan called dextrorphan, the...
- translocation (TET) methylcytosine dioxygenases. They are instrumental in DNA demethylation. 5-Methylcytosine (see first Figure) is a methylated form of the DNA...
- the demethylation pathway shown in the second figure in this section. Altered protein expression in neurons, controlled by ROS-dependent demethylation of...
- the inhibition of memory suppressor genes, and DNA methylation/DNA demethylation was found to be a major mechanism for achieving this dual regulation...
- experience-dependent demethylation response was previously not fully understood, with some evidence showing that DNMTs may be involved in demethylation. It was also...
- in memory formation. ROS also have a central role in epigenetic DNA demethylation, which is relevant to learning and memory In mammalian nuclear DNA,...