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Demethylating agents are
chemical substances that can
inhibit methylation,
resulting in the
expression of the
previously hypermethylated silenced genes...
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including natural products such as
codeine (O-methylmorphine), have been
demethylated by
heating the
substance in
molten pyridine hydrochloride (melting point...
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contribute to the
metabolism of
methamphetamine via an
enzyme which N-
demethylates methamphetamine and 4-hydroxymethamphetamine into
amphetamine and 4-hydroxyamphetamine...
- In enzymology, a Latia-luciferin
monooxygenase (
demethylating) (EC 1.14.99.21) is an
enzyme that
catalyzes the
chemical reaction Latia luciferin + AH2...
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protein shows high
similarity with the
enzyme AlkB
which oxidatively demethylates DNA. FTO is a
member of the
superfamily of alpha-ketoglutarate-dependent...
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Sarcosine oxidase is an
enzyme (EC 1.5.3.1) that
catalyzes the
oxidative demethylation of
sarcosine to
yield glycine, H2O2, 5,10-CH2-tetrahydrofolate in...
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concentrations (EC50 > 20 μM); however, [MDA], the main
psychoactive N-
demethylated phase I
metabolite of MDMA,
potently activated the
receptor at submicromolar...
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creation of a
quaternary ammonium salt,
which is then
dequaternized (
demethylated) in
ethanolamine to
yield DMT. The same two-step
procedure is used to...
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psilocin is
glucuronidated into psilocin-O-glucuronide and
about 4% is
demethylated and
oxidatively deaminated via MAO into 4-HIAL. 4-HIAL is subsequently...
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metabolized by
catechol O-methyltransferase (COMT).
Pseudoephedrine is
demethylated into the
metabolite norpseudoephedrine to a
small extent.
Similarly to...
