-
including natural products such as
codeine (O-methylmorphine), have been
demethylated by
heating the
substance in
molten pyridine hydrochloride (melting point...
-
Demethylating agents are
chemical substances that can
inhibit methylation,
resulting in the
expression of the
previously hypermethylated silenced genes...
-
Sarcosine oxidase is an
enzyme (EC 1.5.3.1) that
catalyzes the
oxidative demethylation of
sarcosine to
yield glycine, H2O2, 5,10-CH2-tetrahydrofolate in...
-
opioid analgesic and the main
active metabolite of tramadol.
Tramadol is
demethylated by the
liver enzyme CYP2D6 to
desmetramadol in the same way as codeine...
-
Asendin among others, is a
tricyclic antidepressant (TCA). It is the N-
demethylated metabolite of loxapine.
Amoxapine first received marketing approval in...
- in the
thesis of Dr. D. L.
Romanowsky in the 1890s), it gets
serially demethylated and
forms all the tri-, di-, mono- and non-methyl intermediates, which...
-
testosterone derivatives:
dihydrotestosterone (DHT)
derivatives 19-
Demethylated testosterone derivatives: 19-nortestosterone (nandrolone) derivatives...
-
singular demethylated narcotine was
called "dimethyl nor-narcotine", the more
demethylated narcotine "methyl nor-narcotine" and the
completely demethylated form...
- it is a derivative.
Norbaeocystin is an N-
demethylated derivative of
baeocystin (itself an N-
demethylated derivative of psilocybin), and a phosphorylated...
-
testosterone derivatives:
dihydrotestosterone (DHT)
derivatives 19-
Demethylated testosterone derivatives: 19-nortestosterone (nandrolone) derivatives...