-
Decitabine (i.e., 5-aza-2′-deoxycytidine), sold
under the
brand name
Dacogen among others, acts as a
nucleic acid
synthesis inhibitor. It is a medication...
-
Decitabine/cedazuridine, sold
under the
brand name
Inqovi among others, is a fixed-dose
combination anticancer medication used for the
treatment of adults...
-
hypomethylating agent decitabine has
shown a
similar survival benefit to
azacitidine and has a
response rate as high as 43%.
Decitabine is
available in combination...
-
Azacitidine Azathioprine Capecitabine Cladribine Clofarabine Cytarabine Decitabine Doxifluridine Fludarabine Fluorouracil Gemcitabine Hydroxyurea Mercaptopurine...
- and RNA.[medical
citation needed]
Azacitidine and its
deoxy derivative,
decitabine (also
known as 5-aza-2′-deoxycytidine) were
first synthesized in Czechoslovakia...
-
myeloid leukemia (AML). For this
purpose it is used with azacitidine,
decitabine, or low-dose
cytarabine for
newly diagnosed adults who are age 75 years...
- DNMT inhibitors).
Currently two
members of the class,
azacitidine and
decitabine, are FDA-approved for use in the
United States in
myelodysplastic syndrome...
-
Cytidine analogs such as 5-azacytidine (azacitidine) and 5-azadeoxycytidine (
decitabine) are the most
commonly used
demethylating agents. They work by inhibiting...
-
Myelodysplastic Syndrome with
Excess Blasts Progressing on or
After Azacitidine or
Decitabine". 29 June 2020. Jost, M (2017). "Combined CRISPRi/a-Based
Chemical Genetic...
-
specializing in oncology, for US$3.9 billion. This
event brought Dacogen (
decitabine),
Aloxi (palonosetron),
Hexalen (altretamine) for
ovarian cancer, and...
