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Debrisoquine is a
derivative of guanidine. It is an
antihypertensive drug
similar to guanethidine.
Debrisoquine is
frequently used for
phenotyping the...
- the
administration of
debrisoquine (a
selective CYP2D6 substrate) and
subsequent plasma concentration ****ay of the
debrisoquine metabolite (4-hydroxydebrisoquine)...
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Urapidil C02CC01
Betanidine C02CC02
Guanethidine C02CC03
Guanoxan C02CC04
Debrisoquine C02CC05
Guanoclor C02CC06
Guanazodine C02CC07
Guanoxabenz C02DA01 Diazoxide...
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Predictions of
metabolic interactions between R-bufuralol, bunitrolol, and
debrisoquine".
Journal of
Pharmaceutical Sciences. 99 (10): 4406–26. doi:10.1002/jps...
-
example (shown below).
antihypertension agents, such as
quinapril and
debrisoquine (all
derived from 1,2,3,4-tetrahydroisoquinoline).
antiretroviral agents...
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atenolol was not
significantly different between "extensive" and "poor
debrisoquine metabolizers" – in
contrast to the
plasma concentrations of metoprolol...
- antihypertensives.
Examples of
these agents include bethanidine, bretylium,
debrisoquine, guanadrel, guanazodine, guancydine, guanethidine, guanoclor, and guanoxan...
- Df–Di | Do | Dr–Dy
deanol aceglumate (INN) Deapril-ST
deboxamet (INN)
debrisoquine (INN)
debropol (INN) Deca-Durabolin
Decabid Decaderm decamethonium bromide...
-
endobiotic inhibitors of
cytochrome P-450dbl function, the
target of the
debrisoquine/sparteine type polymorphism".
Biochemical Pharmacology. 37 (20): 3829–3835...
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concentrations were
higher in four
subjects who were poor
metabolisers of
debrisoquine in
comparison with the four
extensive metabolisers.
Following daily oral...
